http://he-group.uchicago.edu/ WebFTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. N(6)-methyladenosine is a prevalent internal modification in …

Base-resolution sequencing of m6A in RNA - Chuan He

Web( Peer Reviewed Journal Articles: † First Author; * Corresponding Author.) [24] P. Cody He, Jiagnbo Wei, Xiaoyang Dou, Bryan T. Harada, Zijie Zhang, Ruiqi Ge, Chang Liu, Li-Sheng Zhang, Xianbin Yu, Shuai Wang, Ruitu Lyu, Zhoangyu Zou, Mengjie Chen, Chuan He* Exon architecture controls mRNA m6A suppression and gene expression. Science 379, … WebThe FTO gene was identified as an important locus harboring common variants with an unequivocal impact on obesity predisposition and fat mass at the population level. 51,52 Likewise, it was found, in studies concerning large numbers of subjects, that the FTO gene polymorphism is related to higher BMI, as well as weight and abdominal … inception dream levels

FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs

WebMar 25, 2014 · α-ketoglutarate-dependent dioxygenases FTO and ALKBH5 are m 6 A demethylases of mRNA (and other types of nuclear RNA) that affect biological processes such as development, energy homeostasis and... WebNov 15, 2010 · FTO is a DNA and RNA demethylase that affects body mass index and development through an unknown mechanism 18. Although the RNA-processing function of FTO has been suggested to affect gene... WebChuan He is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago.He received his B.S. (1994) from the … income protection for mortgage